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Parenthood is the most beautiful experience a couple can cherish…

And it can be better cherished and valued, when the child is prayed for and awaited. The endurance, longing and despair that come with infertility shall now be put to an end, as we rise with a ray of Hope to fill your life with wonderful laughter of a bundle of joy!

Our infertility specialist and the multidisciplinary team collaborate to ensure that you get the best possible care. The experts are a valuable resource, providing you with a wealth of educational materials and guidance throughout your health care experience. ISHA aims to deliver the highest quality of care, in a friendly and comforting environment and aims at fulfilling the needs of the patients with the best possible care and technology, at par with international standards.

The dearth of services in this field makes it impossible for many to cherish parenthood and Isha aims to change that, with its team of highly skilled doctors and embryologists, combined with state-of-the-art technology and medical facilities. ISHA’s comprehensive range of treatments and strict quality control measures ensure high rate of success.

ISHA Multispeciality hospital imparts a HOPE of creating joy in your life, with many different services which would be successful in bringing a bundle of joy in your life.

ISHA offers the following services

  • IUI (intrauterine insemination)

    IUI or Intrauterine insemination is a technique which involves depositing sperm into a uterus which may or may not result into conception. It is the most commonly used methods of artificial insemination. It is a simple and safe treatment in infertility with an objective of overcoming the natural barriers to the passage of the sperms from the vagina. During IUI, a prepared semen sample is suspended in the uterine cavity. This is done around the predicted time of ovulation.

    There are many stages and processes in the IUI method.

    Ovulation Induction

    Ovulation Induction – in patients where the cause of infertility is anovulaltion. It can be done using a combination of drugs and / or injections.

    Follicular monitoring

    Follicular monitoring – to monitor the development of follicle and endometrium

    Ovulation Trigger

    When follicle reaches 18-20 mm size and endometrial thickness between 8-11 mm, an injection is given for rupture of ovum. IUI can be done after 36 hours of this injection.

    Intrauterine Insemination

    On the day of IUI, semen sample is processed with special media to get good quality sperms, isolated from the abnormal morphological forms, cellular debris and cells. Processed sample is taken in an intra uterine cannula and introduced into the uterine cavity.

    Controlled Ovarian Hyper-stimulation with Intrauterine Insemination:

    • COH IUI is today considered the gold standard for the management of many etiologies including unexplained infertility.
    • The procedure has been performed with excellent results.
    • Help is extended to patients through the availability of fertility inducing drugs at affordable price.

    Indications for IUI

    • Unexplained Infertility
    • Male factor – Mild Oligozoospermia
    • Early and after surgical treatment of Endometriosis
    • Ovulatory dysfunction
    • Cervical factor
    • Immunological Infertility
    • Ejaculatory dysfunction
  • IVF-ET (in-vitro fertilization and embryo transfer)

    In-vitro fertilization (IVF) is a method wherein egg cells are fertilized by sperm outside the woman’s womb in a laboratory dish. IVF is a major treatment in infertility when every other conception method has failed. The process involves removal of a woman’s eggs from the ovaries and fertilizing it with a sperm in a fluid medium. Embryo transfer is performed wherein the fertilized egg is transferred to patient’s uterus to establish a successful pregnancy. Standard IVF is also known as Day 3 transfers, where embryos are placed inside the uterus at a time when they should normally still be in the fallopian tubes.

    In-vitro fertilization

    The preferred mode of treatment, in the presence of tubal factors of infertility are not amenable to routine treatment, where eggs are fertilized by sperms in lab environment.

    Indications for IVF

    • Blocked tubes
    • Mild oligozoospermia
    • Endometriosis, genital tuberculosis
    • Unexplained infertility
  • ICSI (intracytoplasmic sperm injection)

    Direct injection of one sperm into the eggs obtained from in-vitro fertilization (IVF) is known as intra-cytoplasmic sperm injection (ICSI). It is generally recommended when achieving fertilization seems to be difficult. ICSI can facilitate fertilization by sperm that previously could not bind to or penetrate an egg. This is often used in couples dealing with male infertility factors. ICSI success rates are higher than the conventional IVF methods.

    Intracytoplasmic sperm Injection (ICSI)

    The most recent advance in infertility management; ICSI achieves pregnancy by injecting a single sperm into a good quality egg. This is now the preferred modality for the male factor of infertility.

    Indications for ICSI

    • Severe oligozoospermia
    • Oligoasthenoterato zoospermia
    • A zoospermia (Testicular biopsy – to retrieve sperm)

     

    • Failed IVF cycles
    • Epididymal – testicular spermatozoa MESA – TESA
    • Frozen Thawed spermatozoa
  • IMSI (intracytoplasmic morphologically selected sperm injection)

    IMSI treatment for infertility is believed to be very effective amongst all the infertility treatments to date for male factor infertility. This technique involves selection of the best quality sperm cells from a sample provided by the male partner, and directly injecting it into the eggs retrieved from the female partner, thereby increasing the probability that these sperm cells will fertilize the eggs.

  • Blastocyst culture

    With the advent of Blastocyst culture, IVF pregnancy rates have improved and have reduced multiple pregnancy rates. In embryo transfer, 3-4 embryos are transferred which increases the risk of multiple pregnancies, full of dangerous complications. The strongest, healthiest embryos make it to blastocyst stage, which allows the embryologist to transfer fewer embryos; lowering the risk of high order multiples while maintaining high pregnancy rates.

    Blastocyst Culture:

    • The inherent fault of the embryo division is overcome in-vitro by blastocyst culture. The blastocyst is transferred to the uterus on day 4 or 5.
    • Assisted hatching along with blastocyst culture is used for improving success.
  • Cryopreservation

    • Facilities are available for semen freezing and sperm banking. This is useful as a backup during treatment.
    • Cryopreservation of good quality embryos help to dramatically reduce the cost, since they can be utilized in the subsequent cycle.

     

  • Freezing of embryos

    Embryos can be frozen at various times, ranging from one day after fertilization up to five or six days. Many couples take a decision of freezing some of the surplus good quality embryos created during IVF or ICSI treatment and store them for future use. The embryos can be kept healthy and viable for up to ten years. This allows them the opportunity to get pregnant again in the future or for use in a later IVF cycle.

  • Freezing of eggs

    This process is more complicated and delicate than Embryo freezing, as eggs are more prone to damage than embryos during the freezing process. The genetic material inside the egg gets damaged as ice crystals form inside due to freezing.

    Egg Vitrification also known as snap freezing or flash freezing, differs from traditional egg freezing and is considered superior to it. Vitrification is an ultra rapid cooling technique that does not allow time for ice crystals to form. It allows the water inside and surrounding the egg to instantaneously super cool into a solid state with no ice crystal formation at all.

  • Freezing of sperms

    This technique involves freezing of sperms for future use, either in artificial insemination or other fertility treatments or it can be donated. The donated sperms can be stored for 6 months for screening the donor for infections, before it is used in any treatment. There are cases where sperm cells have been frozen and thawed successfully for more than 40 years.

    Many sperms do not survive or get damaged during freezing and hence, there are chances of reduction in quality of sperms. The poor quality of sperms can be used only for ICSI procedure.

  • Semen analysis

    Semen analysis is a test to determine whether a man is infertile, whether the sperms are unable to get a woman pregnant. Semen analysis has many parts and the semen and sperms are tested on a lot of aspects. As the semen consistency varies from day to day and gets affected by certain conditions, the analysis should be performed regularly over a period of month.

  • Egg donation

    The procedure of egg donation involves fertilizing the eggs of a healthy young woman – the egg donor, with the sperms of the patient‟s husband, wherein the resulting embryos are transferred into the patient’s uterus. This is an option for those women who are unable to achieve pregnancy due to advanced reproductive age, genetic abnormalities, previous surgeries and/or other conditions.

  • Embryo donation

    Embryo donation and adoption is the giving and receiving of fertilized eggs (embryos) that are created during the IVF cycle. During the IVF process, many embryos are created which may not be used. The additional embryos may be stored, donated to scientific research or donated to someone who wants to conceive. Embryo donation can provide the opportunity to assist others who want to conceive, by donating available embryos, and giving someone else the chance to start their own family.

  • TESA

    The usual way of producing sperm for use in Assisted Reproductive Technology is manual stimulation. But when the sperm is not ejaculated, the newest of the aspiration techniques is testicular sperm aspiration/extraction (TESA/E). It involves the direct removal of sperm from the testicles, which can be later used, combined with ICSI treatment. There may be many reasons why a TESA/E may needed to be performed, but all involve an inability to produce and ejaculate with sperm sufficient for fertilization.

  • PESA

    Surgical sperm retrieval methods are used when the male has no sperm present in the ejaculate. They are used in combination with the ICSI procedure and one of the options is the PESA technique. During PESA, a needle is inserted into the epididymis and the sperm is withdrawn. Following these procedures, patients may experience discomfort or pain and may have some localized swelling. However, patients who undergo PESA typically may return to work the following day.

  • Assisted hatching

    Assisted hatching is the procedure performed with laser technology, which involves creating a hole in the covering that surrounds the embryo, to aid it in the hatching process, during the IVF treatment. Assisted hatching may be helpful in the infertile couples because their embryos lack sufficient energy to complete the “hatching” process. In addition, hatched embryos implant one day early, which may allow a greater opportunity for implantation to occur.

  • PGD (Pre-implantation genetic diagnosis)

    Pre-implantation Genetic Diagnosis is a technique that has helped hundreds of couples to conceive healthy babies, many after long periods of infertility or with serious genetic diseases in the family. In PGD testing, one or two cells are removed from a day-3 embryo and tested for a specified condition, such as cystic fibrosis or Down’s syndrome. Only those embryos diagnosed as being unaffected or free of a specific disorder will be transferred in the IVF cycle, maximising the chance of a healthy baby.

    Pre-implantation Genetic Diagnosis can be considered if there are any of the following concerns:

    • Risk of having a child with an inherited genetic condition
    • Either partner has a known family history of chromosome rearrangement
    • Previous chromosomal abnormality in a pregnancy
    • Advanced maternal age recurrent miscarriage
    • Repeated embryo transfers without pregnancy
    • If you would find it difficult to consider termination of an affected pregnancy
  • Technology

    ISHA Multispeciality hospital boasts of state-of-the-art Assisted Reproductive Techniques – ART clinic, which is dedicated to assist reproduction with latest technology and expertise.

    ART Setup:

    • Spacious – sparklingly clean lab, Terrazio clad – smooth washable wall-Zender air cleaner where the air in the lab is made germ free.
    • 3D Color Doppler sonography machine for follicular monitoring and uterine – ovarian – endometrial blood flow study.
    • Olympus – made light microscope for semen evaluation.
    • CO2 Incubators (1) Heraus (2) Galaxy
    • Laminar flow work station
    • Separate and specious OT with Ultrasonography machine and portable Boyle’s apparatus for ovum pick up.
    • Oocyte recovery pump.
    • Olympus inverted microscope with Narishige micro manipulator for ICSI.
    • Computerized Embryo Freezing (freeze control) is used for gradual freezing and thawing of sperms and embryo.

    At ISHA Multispeciality hospital, many procedures are undertaken for fertility management. They are:
    To check tubal patency:

    • S.S.graphy – this is a short procedure, to assess tubal patency & mobility & anatomy of the uterine cavity. It is done on 8th or 10th day of menses.
    • H.S.graphy – this study is done using X-Ray.
    • Op.Lapro-hysteroscopy – this test is done under short general anaesthesia, making 2/3 small incisions on abdomen. The patient can be discharged from hospital on the same day of operation.